Prevalence and Significance of Implantation Site Trophoblastic Atypia in Hydatidiform Moles and Spontaneous Abortions

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Ki-67 Expression in Hydatidiform Moles and Hydropic Abortions

BACKGROUND Differential diagnosis of hydatidiform moles from non-molar specimens as well as their sub-classification such as complete and partial hydatidiform moles are important for clinical management and accurate risk assessment for persistent gestational trophoblastic disease, but diagnosis based solely on histomorphology suffers from poor interobserver and intraobserver reproducibility. ...

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ki-۶۷ expression in hydatidiform moles and hydropic abortions

conclusions despite the significant differences , ki-67 immunostaining could not be helpful in distinguishing molar placentas from hydropic abortions as well as partial from complete hydatidiform moles, because there are considerable overlaps between results in different categories. objectives this study was undertaken to determine whether the expression of ki-67 protein could differentiate the...

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Flow Cytometric DNA Analysis and Histopathologic Re-Evaluation of Paraffin Embedded Samples from Hydatidiform Moles and Hydropic Abortions

Background Distinction of hydatidiform moles (HMs) from non-molar abortions and sub-classification of HMs are important for clinical practice; yet, diagnosis based solely on morphology is affected by interobserver variability. The objective of this study was to determine the role of DNA flow cytometry in distinguishing molar from non-molar pregnancies. MaterialsAndMethods This retrospective stu...

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Tetraploidy in hydatidiform moles.

STUDY QUESTION How does tetraploidy develop in hydatidiform moles (HMs), and what is the frequency of the different origins? SUMMARY ANSWER Most molar pregnancies with tetraploid cells appear to be produced by somatic endoreduplications, while a minority originate from a tetraploid zygote. The frequency of zygotic tetraploidy was estimated to be 0.7%. WHAT IS KNOWN ALREADY The parental orig...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 1996

ISSN: 0002-9173,1943-7722

DOI: 10.1093/ajcp/105.4.411